Adaptation of wild-type measles virus to tissue culture.

Adaptation of Horsesickness Virus to Tissue Culture

Replication Characteristics of Herpes Simplex Virus Type-1 (HSV-1) Recombinants in 3 Types of Tissue Cultures

A complication in the analysis of the role of ICP34.5 gene in the herpes simplex virus type-1 (HSV-1) lifecycle is the presence of overlapping antisense gene, open reading frame P (ORF P), which is also deleted in HSV-1 ICP34.5 negative mutants. A HSV-1 wild type strain (17+) ICP34.5/ORF P deletion mutant (1716) is totally avirulent in animal models and impaired in a number of in vitro function...

Adaptation du virus aphteux de type SAT 1 a la culture Frenkel et préparation d'un vaccin saponiné inactivé

Amino Acid substitutions in matrix, fusion and hemagglutinin proteins of wild measles virus for adaptation to vero cells.

BACKGROUND Wild-type measles virus (MV) is isolated in B95a but not in Vero cells. Through an adaptation process of wild-type MV to Vero cells, several amino acid substitutions were reported. METHODS Six strains were adapted to Vero cells and membrane (M), fusion (F) and hemagglutinin (H) genes were sequenced. Cell fusion was assessed and recombinant MVs were constructed, having wild-type H o...

Should We Consider another Booster Dose of Measles Vaccine?

Background: To date, 36 years has passed since the beginning of measles vaccination; the disease is still circulating around the world, threatening lives of human beings especially in developing countries.  In recent years, we have confronted measles in previously vaccinated adults from all over the country. Objective: To find out if there is a need for changing our routine measles vaccination ...